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ULTRA MENOEASE
 | Description: ouglas Laboratories, is a combination of soy isoflavones and the herbs, black cohosh and red clover, carefully formulated and specifically designed to support a woman's healthy and trouble free transition through menopause. Size: 60 | Price: $60.00 |
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Functions:
Isoflavones are a class of phytoestrogens, plant- derived compounds that are similar in structure and/or function to animal estrogens. Although the most well known and significant dietary source of isoflavones is the soybean, another source is red clover, Trifolium pratense. Genistein and daidzein are two predominant isoflavones found in both soy products and red clover. Epidemiological studies have found that individuals with high soy intakes often enjoy certain health advantages. Numerous laboratory and clinical studies, investigating the health benefits of soy products, have identified soy isoflavones as key components responsible for the health benefits associated with soy foods. Isoflavones have both weak estrogenic and anti-estrogenic activity, which may contribute to their ability to moderate menopausal symptoms and support maintenance of bone mineral density. Isoflavones also help protect the cardiovascular system, support the immune system, inhibit angiogenesis, and protect against oxidative damage as antioxidants. Black cohosh, Cimicifuga racemosa, an herb with a long history of use in Native American cultures for gynecological disorders, is currently seen as a natural way to normalize hormonal changes and moderate the uncomfortable symptoms that accompany menopause. Black cohosh works largely through the synergistic activity of two types of compounds: phytoestrogens and triterpenes. Phytoestrogens, a class of flavonoids with mild estrogenic activity in the body, appear to have normalizing effects on hormonal levels. In particular, black cohosh extract contains formononetin, an isoflavone phytoestrogen. Triterpene glycosides found in black cohosh extract act synergistically with formononetin to suppress excessive secretion of luteinizing hormone (LH). Sudden increases in LH secretion, which occur in response to declining estrogen levels, appear largely responsible for many symptoms associated with menopause, such as hot flashes, night sweats, insomnia, irritability, heart palpitations, and headaches. Additionally, the concerted activity of formononetin and triterpenes appears to aid in the regulation of estrogen balance. As with other estrogenic compounds, the active constituents in black cohosh extract may have beneficial effects on the structure and function of the cardiovascular and skeletal systems of postmenopausal women. As such, black cohosh offers a safe and natural method of balancing hormone levels and easing the uncomfortable symptoms of menopause.
Indications:
Ultra-Menoease capsules may be a useful dietary supplement for women who wish to support a healthy transition through menopause.
Formula:
Each Vcapsï›› Vegetarian Capsule Contains: Soy Isoflavones ...........................................100 mg (from 250 mg of Novasoyï›› Isoflavone Concentrate) Proprietary Base Blend..................................75 mg Black Cohosh (standardized) and Red Clover Novasoy is a trademark of the Archer-Daniels- Midland Company
Suggested usage:
Adults take 1 capsule daily or as directed by physician.
Warnings/Side effects:
No adverse effects have been reported.
Storage:
Store in a cool, dry place, away from direct light. Keep out of reach of children. Product Data Douglas Laboratories ® (continued on reverse)
References:
Adlercreutz H, Mazur W. Phyto-oestrogens and Western diseases. Ann Med 1997;29:95-120. Albertazzi P, Pansini F, Bonaccorsi G, Zanotti L, Forini E, De Aloysio D. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998;91:6-11. Baird DD, Umbach DM, Lansdell L, Hughes CL, Setchell KD, Weinberg CR, Haney AF, Wilcox AJ, McLachlan JA. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab 1995;80:1685-90. Barnes S. Evolution of the health benefits of soy isoflavones. Proc Soc Exp Biol Med 1998;217:386-92. Baum JA, Teng H, Erdman JW, Jr., Weigel RM, Klein BP, Persky VW, Freels S, Surya P, Bakhit RM, Ramos E, Shay NF, Potter SM. Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density-lipoprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women. Am J Clin Nutr 1998;68:545-51. Clarkson TB, Anthony MS, Williams JK, Honore EK, Cline JM. The potential of soybean phytoestrogens for postmenopausal hormone replacement therapy. Proc Soc Exp Biol Med 1998;217:365-8. Duker EM, Kopanski L, Jarry H, Wuttke W. Effects of extracts from Cimicifuga racemosa on gonadotropin release in menopausal women and ovariectomized rats. Planta Med 1991;57:420-4. Duncan AM, Underhill KE, Xu X, Lavalleur J, Phipps WR, Kurzer MS. Modest hormonal effects of soy isoflavones in postmenopausal women. J Clin Endocrinol Metab 1999;84:3479-84. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998;7:525-9. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders. Adv Ther 1998;15:45-53. Lock M. Menopause: lessons from anthropology. Psychosom Med 1998;60:410-9. Murkies AL, Lombard C, Strauss BJ, Wilcox G, Burger HG, Morton MS. Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas 1995;21:189-95. Nagata C, Takatsuka N, Inaba S, Kawakami N, Shimizu H. Association of diet and other lifestyle with onset of menopause in Japanese women. Maturitas 1998;29:105-13. Nestel PJ, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West L. Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women. J Clin Endocrinol Metab 1999;84:895-8. Nestel PJ, Yamashita T, Sasahara T, Pomeroy S, Dart A, Komesaroff P, Owen A, Abbey M. Soy isoflavones improve systemic arterial compliance but not plasma lipids in menopausal and perimenopausal women. Arterioscler Thromb Vasc Biol 1997;17:3392-8. Petrakis NL, Barnes S, King EB, Lowenstein J, Wiencke J, Lee MM, Miike R, Kirk M, Coward L. Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women. Cancer Epidemiol Biomarkers Prev 1996;5:785-94. Potter SM, Baum JA, Teng H, Stillman RJ, Shay NF, Erdman JW, Jr. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am J Clin Nutr 1998;68:1375S- 1379S. Ramsey LA, Ross BS, Fischer RG. Phytoestrogens and the management of menopause [In Process Citation]. Adv Nurse Pract 1999;7:26-30. Seidl MM, Stewart DE. Alternative treatments for menopausal symptoms. Systematic review of scientific and lay literature [published erratum appears in Can Fam Physician 1998 Aug;44:1598]. Can Fam Physician 1998;44:1299-308. Washburn S, Burke GL, Morgan T, Anthony M. Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women [see commentss]. Menopause 1999;6:7-13. Whitten PL, Naftolin F. Reproductive actions of phytoestrogens. Baillieres Clin Endocrinol Metab 1998;12:667-90.
Information:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Manufactured:
Manufactured by Douglas Laboratories 600 Boyce Road Pittsburgh, PA 15205 800-245-4440
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