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CHITO-MAX 750
Description: Chito-MAX 750, as chitosan, is an N-deacetylated product of chitin with a minimum 90% degree of deacetylation. Chitosan is a glucosamine polymer derived from crab shells. Size: 120 | Price: $46.40 |
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Functions:
Chito-MAX 750, with chitosan, a natural product produced from the chitin of crab shells, binds strongly to dietary fat and thus can effectively inhibit its absorption from the gastrointestinal tract. As an effective binder of dietary fat, chitosan can be a potent component of a weight control program. The strong positive charge of the chitosan molecule is responsible for its binding to negatively charged lipid molecules. The chitosan molecule's positive charge and associated fat binding efficiency is related to its degree of deacetylation. Thus, a highly deacetylated chitosan product like Chito-MAX 750 has a strong inhibitory effect on fat digestibility. Research has shown that fat digestion and absorption can be reduced further if the dietary chitosan is supplemented with ascorbic acid. Chito-MAX 750 is supplemented with an ascorbic acid preparation to improve its efficacy. Animal studies have also demonstrated that addition of 2 to 5% chitosan to a hypercholesterolemic diet significantly reduced plasma cholesterol 20 to 30% without affecting food intake. The chitosan in this study evidently reduced plasma cholesterol by binding intestinal lipids and increasing fecal excretion of both endogenous and exogenous cholesterol. Later investigation showed that chitosan binds both bile acids and phospholipids, reducing their absorption from the intestines.
Indications:
Chito-MAX 750 capsules may be a useful dietary supplement for those who wish to reduce their absorption of dietary fat and calories.
Formula:
2 Capsules Contain: Chito-MAX (as Chitosan)............................750 mg (In a buffered base of mineral ascorbates, supplying vitamin C)
Suggested usage:
Adults take 1 to 2 capsules before meals 1 to 2 times daily or as directed by physician.
Warnings/Side effects:
No adverse effects have been reported.
Storage:
Store in a cool, dry place, away from direct light. Keep out of reach of children.
References:
Deuchi, K, Kanauchi, O, Imasato, Y, Kobayashi, E. Effect of the viscosity or deacetylation degree of chitosan on fecal fat excreted from rats fed on a high-fat diet. Biosci Biotechnol Biochem 1995;59:781-5. Ebihara, K, Schneeman, BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119:1100-6. Han, LK, Kimura, Y, Okuda, H. Reduction in fat storage during chitin-chitosan treatment in mice fed a high-fat diet. Int J Obes Relat Metab Disord 1999;23:174-9. Kanauchi, O, Deuchi, K, Imasato, Y, Shizukuishi, M, Kobayashi, E. Mechanism for the inhibition of fat digestion by chitosan and for the synergistic effect of ascorbate. Biosci Biotechnol Biochem 1995;59:786-90. LeHoux, JG, Grondin, F. Some effects of chitosan on liver function in the rat. Endocrinology 1993;132:1078-84. Ormrod, DJ, Holmes, CC, Miller, TE. Dietary chitosan inhibits hypercholesterolaemia and atherogenesis in the apolipoprotein E- deficient mouse model of atherosclerosis. Atherosclerosis 1998;138:329-34. Pittler, MH, Abbot, NC, Harkness, EF, Ernst, E. Randomized, double-blind trial of chitosan for body weight reduction. Eur J Clin Nutr 1999;53:379-81. Razdan, A, Pettersson, D. Effect of chitin and chitosan on nutrient digestibility and plasma lipid concentrations in broiler chickens. Br J Nutr 1994;72:277-88. Razdan, A, Pettersson, D. Hypolipidaemic, gastrointestinal and (continued on reverse) Product Data Douglas Laboratories ® related responses of broiler chickens to chitosans of different viscosity. Br J Nutr 1996;76:387-97. Sugano, M, Fujikawa, T, Hiratsuji, Y, Nakashima, K, Fukuda, N, Hasegawa, Y. A novel use of chitosan as a hypocholesterolemic agent in rats. Am J Clin Nutr 1980;33:787-93.
Information:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Manufactured:
Manufactured by Douglas Laboratories 600 Boyce Road Pittsburgh, PA 15205 800-245-4440
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The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Information about each product is taken from the labels of the products or from the manufacturer's advertising material. we are not responsible for any statements or claims that various manufacturers make about their products. We cannot be held responsible for typographical errors or product formulation changes.